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Microplastics accelerate artery fat buildup in mice

Microplastics accelerate artery fat buildup in mice

  • 04/12/2025
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New study: microplastics accelerate fat accumulation in the arteries of male mice.

A new study published in Environment International has found that exposure to microplastics can accelerate fat buildup in the arteries of male mice, a process linked to an increased risk of heart disease.

Researchers observed a significant rise in arterial fat accumulation in male mice exposed to microplastics at doses comparable to those found in natural environments. They also detected changes in cell types and genes involved in this process.

Female mice less affected

In female mice, these effects were not observed. The researchers suggest that oestrogen may offer a protective effect, shielding female arteries from microplastic-induced damage.

Call to action: reduce microplastic exposure

The study reinforces the urgency of reducing human exposure to microplastics. Experts recommend:

  • Avoid heating plastic containers or bottles in the microwave.

  • Do not use plastic tea bags.

  • Be mindful of clothing materials: fast fashion and synthetic fibres release microplastics that can even reach the brain through inhalation.

A global plastic pollution crisis

Microplastics are released from countless everyday products. Clothing, packaging, and household items, contaminating food, water and air worldwide. In August, delegates again met in Geneva to negotiate a global plastics treaty, but talks ended without progress.

Health risks for humans

This research adds to growing evidence that microplastics accumulate in human organs, including the brain, lungs, kidneys, joints and blood vessels. Recent studies show that patients with carotid artery plaque containing microplastics face a higher risk of heart attack, stroke or death within three years.

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